mir-451a-5p Modulates Breast Cancer Cell Apoptosis, Migration, and Chemosensitivity to Carboplatin through the PTEN Pathway

mir-451a-5p Modulates Breast Cancer Cell Apoptosis, Migration, and Chemosensitivity to Carboplatin through the PTEN Pathway

Background: MicroRNAs (miRNAs) can play essential roles in the modulation of cancer cell growth, survival, and resistance to chemotherapy. Thus, we hypothesized that restoration of miR-451a-5p (a tumor suppressor) might affect sensitivity to chemotherapeutics in breast cancer cells. Methods: For thi...

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Main Authors: Monireh Khordadmehr (Author), Hamed Ezzati (Author), Amirali Shahbazfar (Author), Farinaz Jigari-Asl (Author), Behzad Baradaran (Author), Elham Baghbani (Author), Saeed Noorolyai (Author)
Format: Book
Published: Tabriz University of Medical Sciences, 2023-07-01T00:00:00Z.
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