Design of Experiments to Achieve an Efficient Chitosan-Based DNA Vaccine Delivery System

• Main Authors: Carlos Rodolfo (Author), Dalinda Eusébio (Author), Cathy Ventura (Author), Renato Nunes (Author), Helena F. Florindo (Author), Diana Costa (Author), Ângela Sousa (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In current times, DNA vaccines are seen as a promising approach to treat and prevent diseases, such as virus infections and cancer. Aiming at the production of a functional and effective plasmid DNA (pDNA) delivery system, four chitosan polymers, differing in the molecular weight, were studied using...