Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium

• Главные авторы: Marta Narczyk (Автор), Marta Ilona Wojtyś (Автор), Ivana Leščić Ašler (Автор), Biserka Žinić (Автор), Marija Luić (Автор), Elżbieta Katarzyna Jagusztyn-Krynicka (Автор), Zoran Štefanić (Автор), Agnieszka Bzowska (Автор)
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• Опубликовано: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Предметы: article
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Helicobacter pylori represents a global health threat with around 50% of the world population infected. Due to the increasing number of antibiotic-resistant strains, new strategies for eradication of H. pylori are needed. In this study, we suggest purine nucleoside phosphorylase (PNP) as a possible...