Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium

• Main Authors: Marta Narczyk (Author), Marta Ilona Wojtyś (Author), Ivana Leščić Ašler (Author), Biserka Žinić (Author), Marija Luić (Author), Elżbieta Katarzyna Jagusztyn-Krynicka (Author), Zoran Štefanić (Author), Agnieszka Bzowska (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Helicobacter pylori represents a global health threat with around 50% of the world population infected. Due to the increasing number of antibiotic-resistant strains, new strategies for eradication of H. pylori are needed. In this study, we suggest purine nucleoside phosphorylase (PNP) as a possible...