Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats

• Autores principales: Yin-Feng Tan (Autor), Rui-Qi Wang (Autor), Wen-Ting Wang (Autor), Ying Wu (Autor), Ning Ma (Autor), Wei-Ying Lu (Autor), Yong Zhang (Autor), Xiao-Po Zhang (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Context Laurolitsine is an aporphine alkaloid and exhibits potent antihyperglycemic and antihyperlipidemic effects in ob/ob mice. Objective To investigate the pharmacokinetics, tissue distribution and excretion of laurolitsine. Materials and methods A LC-MS/MS method was established and validated to...