Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats

• Main Authors: Yin-Feng Tan (Author), Rui-Qi Wang (Author), Wen-Ting Wang (Author), Ying Wu (Author), Ning Ma (Author), Wei-Ying Lu (Author), Yong Zhang (Author), Xiao-Po Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Laurolitsine is an aporphine alkaloid and exhibits potent antihyperglycemic and antihyperlipidemic effects in ob/ob mice. Objective To investigate the pharmacokinetics, tissue distribution and excretion of laurolitsine. Materials and methods A LC-MS/MS method was established and validated to...