Dex modulates the balance of water-electrolyte metabolism by depressing the expression of AVP in PVN

• Main Authors: Wenzhi Yang (Author), Hao Li (Author), Zhongle Cheng (Author), You Lu (Author), Wuli Li (Author), Jun Feng (Author), Liecheng Wang (Author), Juan Cheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dexmedetomidine (Dex) is a highly selective α2 adrenergic agonist used in clinical anesthesia. Studies have shown that Dex can act on the collecting duct and reduce the body's water reabsorption, thereby increasing water discharge. However, the specific mechanism of Dex on water homeostasis rem...