In vitro and in vivo evaluation of self-assembled chitosan nanoparticles selectively overcoming hepatocellular carcinoma via asialoglycoprotein receptor

• Main Authors: Rensong Sun (Author), Linlin Fang (Author), Xia Lv (Author), Jiani Fang (Author), Yuting Wang (Author), Dapeng Chen (Author), Liang Wang (Author), Jun Chen (Author), Yan Qi (Author), Zeyao Tang (Author), Jianbin Zhang (Author), Yan Tian (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related mortality worldwide. Nowadays, liver-targeting drug delivery system has been proven as a promising strategy for overcoming HCC. Asialoglycoprotein receptor (ASGPR) is an ideal receptor for liver targeting, which is mainly ex...