Intersegment Contacts of Potentially Damaging Variants of Cardiac Sodium Channel

Over 1,500 missense variants of sodium channel hNav1.5, which are reported in the ClinVar database, are associated with cardiac diseases. For most of the variants, the clinical significance is uncertain (VUS), not provided (NP), or has conflicting interpretations of pathogenicity (CIP). Reclassifyin...

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Main Authors: Vyacheslav S. Korkosh (Author), Anastasia K. Zaytseva (Author), Anna A. Kostareva (Author), Boris S. Zhorov (Author)
Format: Book
Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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