Daily co-trimoxazole prophylaxis to prevent mortality in children with complicated severe acute malnutrition: a multicentre, double-blind, randomised placebo-controlled trial

• Main Authors: Prof. James A Berkley, FRCPCH (Author), Moses Ngari, MSc (Author), Johnstone Thitiri, MSc (Author), Laura Mwalekwa, HND (Author), Molline Timbwa, HND (Author), Fauzat Hamid, HND (Author), Rehema Ali, SRN (Author), Jimmy Shangala, BPharm (Author), Neema Mturi, MRCPCH (Author), Kelsey D J Jones, MRCPCH (Author), Hassan Alphan, BSc (Author), Beatrice Mutai, MMed (Author), Victor Bandika, MMed (Author), Twahir Hemed, MMed (Author), Ken Awuondo, MSc (Author), Susan Morpeth, FRACP (Author), Prof. Samuel Kariuki, PhD (Author), Gregory Fegan, PhD (Author)
• Format: Book
• Published: Elsevier, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Children with complicated severe acute malnutrition (SAM) have a greatly increased risk of mortality from infections while in hospital and after discharge. In HIV-infected children, mortality and admission to hospital are prevented by daily co-trimoxazole prophylaxis, despite locally rep...