Epigenetic Marks at the Ribosomal DNA Promoter in Skeletal Muscle Are Negatively Associated With Degree of Impairment in Cerebral Palsy

• Главные авторы: Ferdinand von Walden (Автор), Rodrigo Fernandez-Gonzalo (Автор), Jessica Pingel (Автор), John McCarthy (Автор), Per Stål (Автор), Eva Pontén (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Предметы: article
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Introduction: Cerebral palsy (CP) is the most common motor impairment in children. Skeletal muscles in individuals with CP are typically weak, thin, and stiff. Whether epigenetic changes at the ribosomal DNA (rDNA) promoter are involved in this dysregulation remains unknown.Methods: Skeletal muscle...