Epigenetic Marks at the Ribosomal DNA Promoter in Skeletal Muscle Are Negatively Associated With Degree of Impairment in Cerebral Palsy

• Váldodahkkit: Ferdinand von Walden (Dahkki), Rodrigo Fernandez-Gonzalo (Dahkki), Jessica Pingel (Dahkki), John McCarthy (Dahkki), Per Stål (Dahkki), Eva Pontén (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Introduction: Cerebral palsy (CP) is the most common motor impairment in children. Skeletal muscles in individuals with CP are typically weak, thin, and stiff. Whether epigenetic changes at the ribosomal DNA (rDNA) promoter are involved in this dysregulation remains unknown.Methods: Skeletal muscle...