Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis

• Main Authors: Lincoln Matthew R (Author), DeLuca Gabriele C (Author), Herrera Blanca M (Author), Morrison Katie M (Author), Dyment David A (Author), Ramagopalan Sreeram V (Author), Orton Sarah M (Author), Handunnetthi Lahiru (Author), Chao Michael J (Author), Sadovnick A Dessa (Author), Ebers George C (Author)
• Format: Book
• Published: BMC, 2008-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci <it>HLA-DRB1 </it>and <it>HLA-DQB1 </it>contribute significantly to genetic risk. The MHC class II transactivator (<i...