Predicting gene knockout effects from expression data

• Asıl Yazarlar: Jonathan Rosenski (Yazar), Sagiv Shifman (Yazar), Tommy Kaplan (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2023-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background The study of gene essentiality, which measures the importance of a gene for cell division and survival, is used for the identification of cancer drug targets and understanding of tissue-specific manifestation of genetic conditions. In this work, we analyze essentiality and gene e...