Pragmatic physiologically-based pharmacokinetic modeling to support clinical implementation of optimized gentamicin dosing in term neonates and infants: proof-of-concept

IntroductionModeling and simulation can support dosing recommendations for clinical practice, but a simple framework is missing. In this proof-of-concept study, we aimed to develop neonatal and infant gentamicin dosing guidelines, supported by a pragmatic physiologically-based pharmacokinetic (PBPK)...

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Main Authors: Marika A. de Hoop-Sommen (Author), Joyce E. M. van der Heijden (Author), Jolien J. M. Freriksen (Author), Rick Greupink (Author), Saskia N. de Wildt (Author)
Format: Book
Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
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