Thymoquinone-entrapped chitosan-modified nanoparticles: formulation optimization to preclinical bioavailability assessments

• Main Authors: Iqra Rahat (Author), Syed Sarim Imam (Author), Md. Rizwanullah (Author), Sultan Alshehri (Author), Mohammad Asif (Author), Chandra Kala (Author), Mohamad Taleuzzaman (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The major limitation with the oral administration of most of the phytochemicals is their low aqueous solubility and bioavailability. Thymoquinone (THQ) is one of the most widely used phytochemicals used to treat a variety of diseases. However, strong lipophilic characteristics limit its clinical app...