Clearance of viable Mycobacterium ulcerans from Buruli ulcer lesions during antibiotic treatment as determined by combined 16S rRNA reverse transcriptase /IS 2404 qPCR assay.

• Автори: Mabel Sarpong-Duah (Автор), Michael Frimpong (Автор), Marcus Beissner (Автор), Malkin Saar (Автор), Ken Laing (Автор), Francisca Sarpong (Автор), Aloysius Dzigbordi Loglo (Автор), Kabiru Mohammed Abass (Автор), Margaret Frempong (Автор), Fred Stephen Sarfo (Автор), Gisela Bretzel (Автор), Mark Wansbrough-Jones (Автор), Richard Odame Phillips (Автор)
• Формат: Книга
• Опубліковано: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Buruli ulcer (BU) caused by Mycobacterium ulcerans is effectively treated with rifampicin and streptomycin for 8 weeks but some lesions take several months to heal. We have shown previously that some slowly healing lesions contain mycolactone suggesting continuing infection after antibiotic therapy....