Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells

Regulatory Effects of Apatinib in Combination with Piperine on MDM-2 Gene Expression, Glutathione Peroxidase Activity and Nitric Oxide level as Mechanisms of Cytotoxicity in Colorectal Cancer Cells

Purpose: Apatinib has been utilized in colon cancer therapies but its efficiency and molecularmechanism are not fully understood. Chemotherapy in combination with non-toxic compoundscan be an effective treatment strategy for cancer. Consequently, this study was carried out toevaluate the effects of...

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Main Authors: Mahshid Mohammadian (Author), Zakieh Rostamzadeh Khameneh (Author), Soraya Emamgholizadeh Minaei (Author), Meysam Ebrahimifar (Author), Kosar Esgandari (Author)
Format: Book
Published: Tabriz University of Medical Sciences, 2022-03-01T00:00:00Z.
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