Current Landscape of NRF2 Biomarkers in Clinical Trials

• Glavni autori: Yoko Yagishita (Autor), Tonibelle N. Gatbonton-Schwager (Autor), Melissa L. McCallum (Autor), Thomas W. Kensler (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2020-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by <i>NFE2L2</i>) plays a critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the regulation of inflammation and cellular detoxication pathways. The contribution of the NRF2 pathway to...