TNP and its analogs: Modulation of IP6K and CYP3A4 inhibition

• Váldodahkkit: Seulgi Lee (Dahkki), Bernie Byeonghoon Park (Dahkki), Hongmok Kwon (Dahkki), Vitchan Kim (Dahkki), Jang Su Jeon (Dahkki), Rowoon Lee (Dahkki), Milan Subedi (Dahkki), Taehyeong Lim (Dahkki), Hyunsoo Ha (Dahkki), Dongju An (Dahkki), Jaehoon Kim (Dahkki), Donghak Kim (Dahkki), Sang Kyum Kim (Dahkki), Seyun Kim (Dahkki), Youngjoo Byun (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2022-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Inositol hexakisphosphate kinase (IP6K) is an important mammalian enzyme involved in various biological processes such as insulin signalling and blood clotting. Recent analyses on drug metabolism and pharmacokinetic properties on TNP (N2-(m-trifluorobenzyl), N6-(p-nitrobenzyl)purine), a pan-IP6K inh...