Design, synthesis and anticancer activity studies of 3-(coumarin-3-yl)-acrolein derivatives: Evidenced by integrating network pharmacology and vitro assay

• Main Authors: Lexian Chen (Author), Qianqian Lv (Author), Jianghong Cai (Author), Jiajie Liang (Author), Ziyan Liang (Author), Jiahui Lin (Author), Ying Xiao (Author), Ruiyao Chen (Author), Zhiling Zhang (Author), Yue Hong (Author), Hong Ji (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coumarin derivatives have diverse structures and show various significant biological activities. Aiming to develop more potent coumarin derivatives for cancer treatment, a series of coumarin acrolein hybrids were designed and synthesized by using molecular hybridization approach, and investigated fo...