Preparation of Drug-Loaded Liposomes with Multi-Inlet Vortex Mixers

• Main Authors: Huangliang Zheng (Author), Hai Tao (Author), Jinzhao Wan (Author), Kei Yan Lee (Author), Zhanying Zheng (Author), Sharon Shui Yee Leung (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The multi-inlet vortex mixer (MIVM) has emerged as a novel bottom-up technology for solid nanoparticle preparation. However, its performance in liposome preparation remains unknown. Here, two key process parameters (aqueous/organic flow rate ratio (FRR) and total flow rate (TFR)) of MIVM were invest...