The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms

• Main Authors: Francesca Fasolo (Author), Greg Winski (Author), Zhaolong Li (Author), Zhiyan Wu (Author), Hanna Winter (Author), Julia Ritzer (Author), Nadiya Glukha (Author), Joy Roy (Author), Rebecka Hultgren (Author), Jessica Pauli (Author), Albert Busch (Author), Nadja Sachs (Author), Christoph Knappich (Author), Hans-Henning Eckstein (Author), Reinier A. Boon (Author), Valentina Paloschi (Author), Lars Maegdefessel (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and local inflammation. This condition is often asymptomatic until rupture occurs, leading to high morbidity and mortality rates. Di...