Hedgehog Suppresses Paclitaxel Sensitivity by Regulating Akt-Mediated Phosphorylation of Bax in EGFR Wild-Type Non-Small Cell Lung Cancer Cells

• Główni autorzy: Yun-Chieh Tu (Autor), Wei-Chen Yeh (Autor), Hsin-Hsien Yu (Autor), Yu-Cheng Lee (Autor), Bor-Chyuan Su (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Non-small cell lung cancer (NSCLC) is one of the most common and deadly cancers worldwide. Among NSCLC patients, almost half have wild-type epidermal growth factor receptor (EGFR WT). The primary therapeutic option for these EGFR WT NSCLC patients is chemotherapy, while NSCLC patients with EGFR muta...