Marine Sponge Xestospongia sp.: A Promising Source for Tuberculosis Drug Development - Computational Insights into Mycobactin Biosynthesis Inhibition

• Main Authors: Arfan Arfan (Author), Aiyi Asnawi (Author), La Ode Aman (Author)
• Format: Book
• Published: Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mycobacterium tuberculosis (MTB) remains the leading cause of infection, with a significant fatality rate, owing primarily to drug resistance. MTB contains the enzyme salicylate synthase, which regulates mycobactin production to bind iron ions from the host cell, facilitating the bacteria to grow an...