The AMP-Dependent Protein Kinase (AMPK) Activator A-769662 Causes Arterial Relaxation by Reducing Cytosolic Free Calcium Independently of an Increase in AMPK Phosphorylation

The AMP-Dependent Protein Kinase (AMPK) Activator A-769662 Causes Arterial Relaxation by Reducing Cytosolic Free Calcium Independently of an Increase in AMPK Phosphorylation

Although recent studies reveal that activation of the metabolic and Ca2+ sensor AMPK strongly inhibits smooth muscle contraction, there is a paucity of information about the potential linkage between pharmacological AMPK activation and vascular smooth muscle (VSM) contraction regulation. Our aim was...

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Bibliographic Details
Main Authors: Yi Huang (Author), Corey A. Smith (Author), Grace Chen (Author), Bharti Sharma (Author), Amy S. Miner (Author), Robert W. Barbee (Author), Paul H. Ratz (Author)
Format: Book
Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
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