Mefloquine--an aminoalcohol with promising antischistosomal properties in mice.

• Main Authors: Jennifer Keiser (Author), Jacques Chollet (Author), Shu-Hua Xiao (Author), Jin-Yan Mei (Author), Pei-Ying Jiao (Author), Jürg Utzinger (Author), Marcel Tanner (Author)
• Format: Bog
• Udgivet: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

BACKGROUND: The treatment and control of schistosomiasis, an often neglected tropical disease that exacerbates poverty, depends on a single drug, praziquantel. The large-scale use of praziquantel might select for drug-resistant parasites, hence there is a need to develop new antischistosomal compoun...