Enhanced drug delivery and wound healing potential of berberine-loaded chitosan-alginate nanocomposite gel: characterization and in vivo assessment

• Main Authors: Md Habban Akhter (Author), Lamya Ahmad Al-Keridis (Author), Mohd Saeed (Author), Habibullah Khalilullah (Author), Safia Obaidur Rab (Author), Adel M. Aljadaan (Author), Mohammad Akhlaquer Rahman (Author), Mariusz Jaremko (Author), Abdul-Hamid Emwas (Author), Sarfaraz Ahmad (Author), Nawazish Alam (Author), Md Sajid Ali (Author), Gyas Khan (Author), Obaid Afzal (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine-encapsulated polyelectrolyte nanocomposite (BR-PolyET-NC) gel was developed as a long-acting improved wound healing therapy. BR-PolyET-NC was developed using an ionic gelation/complexation method and thereafter loaded into Carbopol gel. Formulation was optimized using Design-Expert® softwa...