Cover Image

Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice

The receptor activator of NF-κB ligand (RANKL) and its receptor RANK are overexpressed in focal segmental glomerular sclerosis (FSGS), IgA nephropathy (IgAN), and membranous nephropathy (MN). However, the expression and the potential roles of RANKL and RANK in diabetic nephropathy (DN) remain unclea...

Full description

Saved in:

Bibliographic Details
Main Authors:	Xiao-Wen Chen (Author), Xiao-Yan Du (Author), Yu-Xian Wang (Author), Jian-Cheng Wang (Author), Wen-Ting Liu (Author), Wen-Jing Chen (Author), Hong-Yu Li (Author), Fen-Fen Peng (Author), Zhao-Zhong Xu (Author), Hong-Xin Niu (Author), Hai-Bo Long (Author)
Format:	Book
Published:	Hindawi Limited, 2016-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Corrigendum to "Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice"
by: Xiao-Wen Chen, et al.
Published: (2016)

Zuogui Wan ameliorates high glucose-induced podocyte apoptosis and improves diabetic nephropathy in db/db mice
by: Bingbing Zhu, et al.
Published: (2022)

Network pharmacology and experimental investigation of the protective effect of Shuxuetong injection against diabetic nephropathy and encephalopathy in db/db mice
by: Jia Liu, et al.
Published: (2024)

Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic Db/Db Mice
by: Zhang X, et al.
Published: (2020)

Protective Effects and Mechanisms of Polyethylene Glycol Loxenatide Against Hyperglycemia and Liver Injury in db/db diabetic Mice
by: Yu Zhang, et al.
Published: (2021)

Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway
by: Fujing Wang, et al.
Published: (2022)

The Hypoglycemic and Renal Protection Properties of Crocin via Oxidative Stress-Regulated NF-κB Signaling in db/db Mice
by: Ye Qiu, et al.
Published: (2020)

Dapagliflozin Ameliorates Diabetic Kidney Disease via Upregulating Crry and Alleviating Complement Over-activation in db/db Mice
by: Dong-Yuan Chang, et al.
Published: (2021)

Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice
by: Panshuang Qiao, et al.
Published: (2022)

Effect of echinacoside on kidney fibrosis by inhibition of TGF-β1/Smads signaling pathway in the db/db mice model of diabetic nephropathy
by: Tang FJ, et al.
Published: (2017)

Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway
by: Lu Shi, et al.
Published: (2022)

Polydatin Alleviates Diabetes-Induced Hyposalivation through Anti-Glycation Activity in db/db Mouse
by: Hyung Rae Kim, et al.
Published: (2021)

Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway
by: Jun Wang, et al.
Published: (2022)

9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
by: Yan-Mei Wang, et al.
Published: (2021)

Corrigendum: 9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
by: Yan-Mei Wang, et al.
Published: (2022)

Identification of Key Biomarkers and Immune Infiltration in Sciatic Nerve of Diabetic Neuropathy BKS-db/db Mice by Bioinformatics Analysis
by: Yixuan Lin, et al.
Published: (2021)

Diabetes (<it>db/db</it>) mutation-induced endometrial epithelial lipoapoptosis: Ultrastructural and cytochemical analysis of reproductive tract atrophy
by: Garris David R
Published: (2005)

Dehydro-Tocotrienol-β Counteracts Oxidative-Stress-Induced Diabetes Complications in <i>db/db</i> Mice
by: Gustav Dallner, et al.
Published: (2021)

Huangqi decoction ameliorates kidney injury in db/db mice by regulating the BMP/Smad signaling pathway
by: Ying Chen, et al.
Published: (2023)

Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice
by: Jeong-Won Kim, et al.
Published: (2024)

Penthorum chinense Pursh improves type 2 diabetes mellitus via modulating gut microbiota in db/db mice
by: Jilei Hu, et al.
Published: (2023)

Nobiletin ameliorates glucose tolerance by protecting against β-cell loss in type-2 diabetic db/db mice
by: Yukiko K. Kaneko, et al.
Published: (2022)

Zishen Pill alleviates diabetes in Db/db mice via activation of PI3K/AKT pathway in the liver
by: You Wu, et al.
Published: (2022)

Therapeutic Potential of Exosomes Derived from Diabetic Adipose Stem Cells in Cutaneous Wound Healing of <i>db/db</i> Mice
by: Hsiang-Hao Hsu, et al.
Published: (2022)

The Different Roles of miRNA-92a-2-5p and let-7b-5p in Mitochondrial Translation in db/db Mice
by: Huaping Li, et al.
Published: (2019)

Olmesartan Prevents Microalbuminuria in db/db Diabetic Mice Through Inhibition of Angiotensin II/p38/SIRT1-Induced Podocyte Apoptosis
by: Junhui Gu, et al.
Published: (2016)

Fufang Zhenzhu Tiaozhi capsule attenuates renal damage by restoring Th17/Treg balance in diabetic db/db mice
by: Yiqi YANG, et al.
Published: (2022)

Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice
by: Sing-Young Chen, et al.
Published: (2023)

Enhanced Activity by NKCC1 and Slc26a6 Mediates Acidic pH and Cl− Movement after Cardioplegia-Induced Arrest of db/db Diabetic Heart
by: Minjeong Ji, et al.
Published: (2019)

Gut microbiota mediated hypoglycemic effect of Astragalus membranaceus polysaccharides in db/db mice
by: Qianbo Song, et al.
Published: (2022)

Agriophyllum Oligosaccharides Ameliorate Diabetic Insulin Resistance Through INS-R/IRS/Glut4-Mediated Insulin Pathway in db/db Mice and MIN6 Cells
by: Shuyin Bao, et al.
Published: (2021)

Berberine enhances the function of db/db mice islet β cell through GLP-1/GLP-1R/PKA signaling pathway in intestinal L cell and islet α cell
by: Wenbin Wu, et al.
Published: (2023)

Glucose, insulin, insulin receptor subunits α and β in normal and spontaneously diabetic and obese ob/ob and db/db infertile mouse testis and hypophysis
by: R.-Marc Pelletier, et al.
Published: (2020)

Anti-diabetic effect of black ginseng extract by augmentation of AMPK protein activity and upregulation of GLUT2 and GLUT4 expression in db/db mice
by: Ok-Hwa Kang, et al.
Published: (2017)

Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice
by: Nuria Ardaiz, et al.
Published: (2021)

Effects of D-Chiro-Inositol on Glucose Metabolism in db/db Mice and the Associated Underlying Mechanisms
by: Chunxue Fan, et al.
Published: (2020)

Olmesartan Medoxomil, An Angiotensin II-Receptor Blocker, Ameliorates Renal Injury In db/db Mice
by: Zhu Y, et al.
Published: (2019)

A multi‐omics approach to overeating and inactivity‐induced muscle atrophy in db/db mice
by: Takuro Okamura, et al.
Published: (2024)

Evidence against a role for NLRP3-driven islet inflammation in db/db mice
by: H.L. Kammoun, et al.
Published: (2018)

Diabetes-Induced Central Cholinergic Neuronal Loss and Cognitive Deficit Are Attenuated by Tacrine and a Chinese Herbal Prescription, Kangen-Karyu: Elucidation in Type 2 Diabetes db/db Mice
by: Qi Zhao, et al.
Published: (2011)