Characterization of Domiphen Bromide as a New Fast-Acting Antiplasmodial Agent Inhibiting the Apicoplastidic Methyl Erythritol Phosphate Pathway

• मुख्य लेखकों: Arnau Biosca (लेखक), Miriam Ramírez (लेखक), Alex Gomez-Gomez (लेखक), Aritz Lafuente (लेखक), Valentín Iglesias (लेखक), Oscar J. Pozo (लेखक), Santiago Imperial (लेखक), Xavier Fernàndez-Busquets (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The evolution of resistance by the malaria parasite to artemisinin, the key component of the combination therapy strategies that are at the core of current antimalarial treatments, calls for the urgent identification of new fast-acting antimalarials. The apicoplast organelle is a preferred target of...