Evaluation of mRNA expression of the transcription factors of Th1 and Th2 subsets (T-bet and GATA-3) in periodontal health and disease - A pilot study in south Indian population

• Main Authors: Nichenametla Rajesh (Author), Kurumathur Vasudevan Arun (Author), Tirumelveli Saravanan Subbu Kumar (Author), Kondareddy Krishna Mohan Reddy (Author), Swarna Alamelu (Author), Bhimavarapu Ravinder Reddy (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Based on their respective pro- or anti-inflammatory cytokine profiles, the Th1/Th2 paradigm explains pathogenic mechanisms involved in periodontal disease. Establishment of Th1 and Th2 subsets from a naive T-cell precursor depends on transcriptional regulation. The aim of this study was...