The dual role of FSP1 in programmed cell death: resisting ferroptosis in the cell membrane and promoting necroptosis in the nucleus of THP-1 cells

• Main Authors: Xiaoqian Tan (Author), Yinling He (Author), Panpan Yu (Author), Yunong Deng (Author), Zhongcheng Xie (Author), Jiami Guo (Author), Qin Hou (Author), Pin Li (Author), Xiaoyan Lin (Author), Siyu Ouyang (Author), Wentao Ma (Author), Yushu Xie (Author), Zilong Guo (Author), Dandan Chen (Author), Zhixia Zhang (Author), Yunyu Zhu (Author), Fei Huang (Author), Ziye Zhao (Author), Cen Zhang (Author), Zhirong Guo (Author), Xi Chen (Author), Tianhong Peng (Author), Liang Li (Author), Wei Xie (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Acute monocytic leukemia-M5 (AML-M5) remains a challenging disease due to its high morbidity and poor prognosis. In addition to the evidence mentioned earlier, several studies have shown that programmed cell death (PCD) serves a critical function in treatment of AML-M5. However,...