High mobility group box 1 inhibition by BoxA attenuates ovalbumin-induced allergic rhinitis in mice

• Main Authors: Liyan Yue (Author), Jinhui Dong (Author), Jianxing Wang (Author), Xiaoyan Yin (Author), Xiumin Ren (Author), Ou Xu (Author), Chunguang Shan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was designed to evaluate the effects of BoxA on allergic rhinitis (AR). Ovalbumin (OVA)-induced AR mice model was employed and BoxA was administered to AR mice. AR symptoms, levels of cytokines and chemokines, and the expression of high mobility group box 1 (HMGB1), TLR2, and TLR4 were me...