Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect Against Acute Kidney Injury Through Anti-Oxidation by Enhancing Nrf2/ARE Activation in Rats

• Main Authors: Guangyuan Zhang (Author), Xiangyu Zou (Author), Yeqing Huang (Author), Feng Wang (Author), Shuai Miao (Author), Guohua Liu (Author), Ming Chen (Author), Yingjian Zhu (Author)
• Format: Book
• Published: Karger Publishers, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Anti-oxidation is an effective strategy for curing acute kidney injury (AKI). Herein, we suggest that extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) might play an anti-oxidative role by enhancing Nrf2/ARE activation in AKI. Methods: EVs isolated from the...