Telomere length, oxidative and epigenetic changes in blood DNA of patients with exacerbated psoriasis vulgaris

• Main Authors: Martin Beranek (Author), Pavel Borsky (Author), Zdenek Fiala (Author), Ctirad Andrys (Author), Kvetoslava Hamakova (Author), Marcela Chmelarova (Author), Helena Kovarikova (Author), Adam Karas (Author), Jan Kremlacek (Author), Vladimir Palicka (Author), Lenka Borska (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The pathogenesis of psoriasis vulgaris involves changes in DNA molecules, genomic instability, telomere attrition, and epigenetic alterations among them. These changes are also considered important mechanisms of aging in cells and tissues. Objective This study dealt with oxidatio...