Pharmacogenetics of Osteoporosis: A Pathway Analysis of the Genetic Influence on the Effects of Antiresorptive Drugs

• Autors principals: Álvaro del Real (Autor), Carmen Valero (Autor), José M. Olmos (Autor), Jose L. Hernández (Autor), José A. Riancho (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-04-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Osteoporosis is a skeletal disorder defined by a decreased bone mineral density (BMD) and an increased susceptibility to fractures. Bisphosphonates and selective oestrogen receptor modulators (SERM) are among the most widely used drugs. They inhibit bone resorption by targeting the mevalonate and oe...