Investigating adverse genomic and regulatory changes caused by replacement of the full-length CFTR cDNA using Cas9 and AAV

A "universal strategy" replacing the full-length CFTR cDNA may treat >99% of people with cystic fibrosis (pwCF), regardless of their specific mutations. Cas9-based gene editing was used to insert the CFTR cDNA and a truncated CD19 (tCD19) enrichment tag at the CFTR locus in airway basal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sriram Vaidyanathan (Author), Jenny L. Kerschner (Author), Alekh Paranjapye (Author), Vrishti Sinha (Author), Brian Lin (Author), Tracy A. Bedrosian (Author), Adrian J. Thrasher (Author), Giandomenico Turchiano (Author), Ann Harris (Author), Matthew H. Porteus (Author)
Formato: Livro
Publicado em: Elsevier, 2024-03-01T00:00:00Z.
Assuntos:
Acesso em linha:Connect to this object online.
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Internet

Connect to this object online.

3rd Floor Main Library

Detalhes do Exemplar 3rd Floor Main Library
Área/Cota: A1234.567
Cód. Barras: 1 Disponível