Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway

• Main Authors: Géranton Sandrine M (Author), Tochiki Keri K (Author), Chiu Winnie WY (Author), Stuart Sarah A (Author), Hunt Stephen P (Author)
• Format: Book
• Published: SAGE Publishing, 2010-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Descending controls originating in part from the rostral ventromedial medulla (RVM) regulate the excitability of dorsal horn neurons and maintain peripheral pain states. Activation of extracellular signal regulated kinase (ERK) in RVM neurons has been shown follo...