Piecing together human adult comparative pharmacokinetic trials and rodent studies: What happens to drug clearance in obesity?
In many comparative trials examining the effects of adult obesity on pharmacokinetics of drugs, conclusions were made based on values that were either not adjusted to total body weight or adjusted to non-obese body mass (e.g., ideal or lean body weight). In many cases these values were higher in the...
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Frontiers Media S.A.,
2022-01-01T00:00:00Z.
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A1234.567 |
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