RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory
RNASET2 deficiency in humans is associated with infant cystic leukoencephalopathy, which causes psychomotor impairment, spasticity and epilepsy. A zebrafish mutant model suggests that loss of RNASET2 function leads to neurodegeneration due to the accumulation of non-degraded RNA in the lysosomes. Th...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2018-06-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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