Influence of protein fold stability on immunogenicity and its implications for vaccine design

• मुख्य लेखकों: Sandra Scheiblhofer (लेखक), Josef Laimer (लेखक), Yoan Machado (लेखक), Richard Weiss (लेखक), Josef Thalhamer (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2017-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: In modern vaccinology and immunotherapy, recombinant proteins more and more replace whole organisms to induce protective or curative immune responses. Structural stability of proteins is of crucial importance for efficient presentation of antigenic peptides on MHC, which plays a decisi...