Tobacco-Derived Lipopolysaccharide, Not Microbial Translocation, as a Potential Contributor to the Pathogenesis of Rheumatoid Arthritis

• Main Authors: Pieter W. A. Meyer (Author), Mahmood M. T. M. Ally (Author), Mohammed Tikly (Author), Gregory Tintinger (Author), Lai Ling Winchow (Author), Helen Steel (Author), Ronald Anderson (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Microbial lipopolysaccharides (LPS) have been implicated in the pathogenesis of rheumatoid arthritis (RA), possibly driving a systemic inflammatory response that may trigger the development and/or exacerbation of the disease. To explore the existence of this mechanism in African RA patients, we have...