Synergistic Effects of Erzhi Pill Combined With Methotrexate on Osteoblasts Mediated via the Wnt1/LRP5/β-Catenin Signaling Pathway in Collagen-Induced Arthritis Rats

• Main Authors: Xiaoya Li (Author), Xiangcheng Lu (Author), Danping Fan (Author), Li Li (Author), Cheng Lu (Author), Yong Tan (Author), Ya Xia (Author), Hongyan Zhao (Author), Miaoxuan Fan (Author), Cheng Xiao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by chronic synovitis, bone erosion, and bone loss. Erzhi Pill (EZP), a classic Chinese patent medicine, is often used to treat osteoporosis and shows a capacity for bone metabolism regulation. Methotrexate (MTX), an ess...