The Mechanistic Differences in HLA-Associated Carbamazepine Hypersensitivity

• Główni autorzy: Gwendolin S. Simper (Autor), Lareen S. Gräser (Autor), Alexander A. Celik (Autor), Joachim Kuhn (Autor), Heike Kunze-Schumacher (Autor), Gia-Gia T. Hò (Autor), Rainer Blasczyk (Autor), Andreas Pich (Autor), Christina Bade-Doeding (Autor)
• Format: Książka
• Wydane: MDPI AG, 2019-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Drug hypersensitivity reactions that resemble acute immune reactions are linked to certain human leucocyte antigen (HLA) alleles. Severe and life-threatening Stevens Johnson Syndrome and Toxic Epidermal Necrolysis following treatment with the antiepileptic and psychotropic drug Carbamazepine are ass...