Methyl lucidone induces apoptosis and G2/M phase arrest via the PI3K/Akt/NF-κB pathway in ovarian cancer cells

• Main Authors: Jae-Hwan Yoon (Author), Jong-Woon Shin (Author), Thu-Huyen Pham (Author), Youn-Jin Choi (Author), Hyung-Won Ryu (Author), Sei-Ryang Oh (Author), Jae-Wook Oh (Author), Do-Young Yoon (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown. Objective This study evaluates the mechanism of ML-induced apoptosis, cell cycle distribu...