Building in-house PBPK modelling tools for oral drug administration from literature information

• Prif Awduron: Silvia Grandoni (Awdur), Nicola Cesari (Awdur), Giandomenico Brogin (Awdur), Paola Puccini (Awdur), Paolo Magni (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: International Association of Physical Chemists (IAPC), 2019-02-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

The interest in using physiologically-based pharmacokinetic (PBPK) models as a support to the drug development decision making process has rapidly increased in the last years. These kind of models are examples of the "bottom up" modelling strategy, which progressively integrates into a mec...