Anti-fibrotic Potential of AT2 Receptor Agonists

• Autores principales: Yan Wang (Autor), Mark Del Borgo (Autor), Huey W. Lee (Autor), Dhaniel Baraldi (Autor), Baydaa Hirmiz (Autor), Tracey A. Gaspari (Autor), Kate M. Denton (Autor), Marie-Isabel Aguilar (Autor), Chrishan S. Samuel (Autor), Robert E. Widdop (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

There are a number of therapeutic targets to treat organ fibrosis that are under investigation in preclinical models. There is increasing evidence that stimulation of the angiotensin II type 2 receptor (AT2R) is a novel anti-fibrotic strategy and we have reviewed the published in vivo preclinical da...