Anti-fibrotic Potential of AT2 Receptor Agonists

• Main Authors: Yan Wang (Author), Mark Del Borgo (Author), Huey W. Lee (Author), Dhaniel Baraldi (Author), Baydaa Hirmiz (Author), Tracey A. Gaspari (Author), Kate M. Denton (Author), Marie-Isabel Aguilar (Author), Chrishan S. Samuel (Author), Robert E. Widdop (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There are a number of therapeutic targets to treat organ fibrosis that are under investigation in preclinical models. There is increasing evidence that stimulation of the angiotensin II type 2 receptor (AT2R) is a novel anti-fibrotic strategy and we have reviewed the published in vivo preclinical da...