S-Benproperine, an Active Stereoisomer of Benproperine, Suppresses Cancer Migration and Tumor Metastasis by Targeting ARPC2

• Main Authors: Hyun-Jin Jang (Author), Yae Jin Yoon (Author), Jiyeon Choi (Author), Yu-Jin Lee (Author), Sangku Lee (Author), Wansang Cho (Author), Wan Gi Byun (Author), Seung Bum Park (Author), Dong Cho Han (Author), Byoung-Mog Kwon (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastasis, in which cancer cells migrate to other tissues and form new tumors, is a major cause of both cancer death and treatment failure. In a previous study, benproperine (Benp) was identified as a cancer cell migration inhibitor and an inhibitor of actin-related protein 2/3 complex subunit 2 (A...