Propofol and α2-Agonists Attenuate Microglia Activation and Restore Mitochondrial Function in an In Vitro Model of Microglia Hypoxia/Reoxygenation

• Main Authors: Lucia Longhitano (Author), Alfio Distefano (Author), Paolo Murabito (Author), Marinella Astuto (Author), Anna Nicolosi (Author), Giovanni Buscema (Author), Filippo Sanfilippo (Author), Giuseppe Lazzarino (Author), Angela Maria Amorini (Author), Andrea Bruni (Author), Eugenio Garofalo (Author), Daniele Tibullo (Author), Giovanni Li Volti (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cerebrovascular ischemia is a common clinical disease encompassing a series of complex pathophysiological processes in which oxidative stress plays a major role. The present study aimed to evaluate the effects of Dexmedetomidine, Clonidine, and Propofol in a model of hypoxia/reoxygenation injury. Mi...