Signal Detection Study Focusing on Differences in the Drug Delivery System of Oral 5-Aminosalicylate for Inflammatory Bowel Disease Using the Japanese Pharmacovigilance Database

• Main Authors: Yoshihiro Noguchi (Author), Shuji Yamashita (Author), Hirofumi Tamaki (Author), Arihiro Osanai (Author), Yoko Ino (Author), Tomoya Tachi (Author), Kazuhiro Iguchi (Author), Hitomi Teramachi (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although 5-Aminosalicylate (5-ASA) has been shown to act on the local mucosa, when 5-ASA is orally administered, most of it is absorbed in the upper gastrointestinal tract and does not reach the large intestine, where lesions are present. Therefore, different drug delivery systems have been develope...