Comparison of tape stripping with the human skin blanching assay for the bioequivalence assessment of topical clobetasol propionate formulations.

• Main Authors: Wai Ling Au (Author), Michael F Skinner (Author), Isadore Kanfer (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2010-01-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Purpose: A draft guidance on tape stripping for assessing the bioavailability/bioequivalence of topical formulations was issued by the United States Food and Drug Administration in 1998 but has since been withdrawn. This was due to problems associated with the method and also inconsistencies and var...